PEBC EE

PEBC EE Question Set #15

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By Dhruv Mangukia

Struggling to pass the PEBC EE Evaluating Exam? Don’t worry! This series provides solved questions and strategies mimicking the real exam format, helping you conquer your PEBC exam preparation. We’ll cover realistic scenarios you might face as a pharmacist and guide you through medication order evaluation step-by-step. Test your knowledge with PEBC EE styled questions and gain confidence for your PEBC EE evaluating exam. Let’s ace your PEBC EE exam together!

Questions 1 – 10 to crack the PEBC EE

Question 1: A 55-year-old patient with hypertension is prescribed perindopril as part of their treatment plan. Which of the following is a known side effect of initiating perindopril therapy?

A) Flushing
B) Angioedema
C) Headache
D) Diarrhea
E) All of the above
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Answer: B

Question 2: A retail company has reported its financials for the fiscal year. The total sales amount to $530,000, while the cost of goods sold (COGS) is $350,000. What is the percentage of the gross margin?

A) 10%
B) 20%
C) 25%
D) 30%
E) 34%
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Answer: E

Question 3: A 62-year-old patient undergoing chemotherapy for cancer treatment reports experiencing several side effects, including diarrhea, nausea, and abdominal cramps. Which of the following symptoms should be of most concern?

A) Blood in stool
B) More than 4 stools daily
C) Nausea lasting more than 4 hours
D) Abdominal cramping for more than 10 days
E) All of the above
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Answer: A

Question 4: A 45-year-old patient, diagnosed with arthritis, started taking NSAIDs for pain relief and has been experiencing daily heartburn symptoms.

A) Ranitidine
B) Prednisone
C) Cimetidine
D) Antacid
E) Omeprazole
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Answer: E

Question 5: Endocarditis is caused most commonly by which of the following organisms?

A) Gram positive streptococci
B) Gram negative streptococci
C) Gram positive staphylococci
D) Gram positive Enterococci
E) Gram negative Enterococci
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Answer: C

The Gram-positive bacteria staphylococci 40%, streptococci 20%, and enterococci 10% account for the majority of pathogens causing endocarditis.

Question 6: Which of the following is the correct statement for rheumatoid arthritis?

A) Symmetric joint pain lasting less than 45 minutes and low-grade fever.
B) Occurrence exclusively in weight-bearing joints.
C) Obesity not being a risk factor.
D) Predominantly affecting the elderly population.
E) Involving primarily the large joints such as hips and shoulders.
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Answer: A

Symmetric, for more than 45 minutes in the morning, there is fever, inflammation, and swelling. Happens in both weight-bearing and non-bearing. Obesity is a risk factor.

Question 7: A 60-year-old woman with cancer has been taking hydromorphone for pain management. She is now in the hospital experiencing additional pain and was administered morphine, but she reports no relief. What could be the reason for the lack of response to morphine?

A potentiation
B addiction
C tolerance
D resistance
E toxic effect
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Answer: C

Question 8: An adult female 42 years old has urinary incontinence. She said it has been very bothersome lately and that she could not go out without worrying about if she does not find a toilet. She also added that there is leakage when she coughs or exercises & she has been stressed for the past few days, what kind of urinary incontinence?

A) Stress incontinence
B) Urge incontinence
C) Overflow incontinence
D) Functional incontinence
E) All of the above
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Answer: A

Question 9: What is it called whereby a pharmacist can ethically refuse to fill a prescription for moral or religious reasons?

a) personal clause
b) notwithstanding clause
c) conscience clause
d) freedom of faith clause
e) mutual respect clause
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Answer: C

Question 10: Ketoacidosis means all of the following except?

a) Hypoglycemia
b) Volume depletion (depleted in Sodium, Potassium, Chloride and water)
c) Acidosis
d) Depressed levels of consciousness
e) Detectable ketones in the urine or blood
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Answer: A

Ketoacidosis is treated by administering insulin and fluids.

PEBC Evaluating Exam Practice Questions 11-20

Question 11: A membrane is placed between two solutions with different concentrations of solute and solvent. What happens?

A) Solute moves from a region of lower concentration to a region of higher concentration
B) Solute moves from a region of higher concentration to a region of lower concentration
C) Solvent moves from a region of lower concentration to a region of higher concentration
D) Solvent moves from a region of higher concentration to a region of lower concentration
E) No movement occurs
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Answer: C

Question 12: A 65-year-old patient with chronic obstructive pulmonary disease (COPD) is currently being treated with erythromycin for a bacterial infection. The treating physician is considering adding another antibiotic to the regimen. Which of the following antibiotics can be safely added to his treatment plan?

A) Ciprofloxacin
B) Levofloxacin
C) Clindamycin
D) Amoxicillin
E) Azithromycin
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Answer: B

Question 13: You are a pharmacy manager and have two pharmacists working at the pharmacy, you figured that there is a shortage of Meperidine stock, so you set up a surveillance camera and figure out the one who took this narcotic. what is the appropriate action?

A) Call the pharmacist who was involved in the incidence
B) As a pharmacy manager, use your authority and fire him.
C) Call the regulatory college and report the case
D) Call the Royal Canadian Mounted Police RCMP
E) Report the incidence to the Office of Controlled Substances
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Answer: D

ScenarioActionFollow-up
Misconduct by colleagueReport directly to the College of PharmacyNot applicable
Incompetent pharmacist at another pharmacyReport to their managerMaintain contact to learn the outcome
Prescription forgery or stolen narcoticsCall the Royal Canadian Mounted Police (RCMP) immediatelyReport to the College of Pharmacy within 10 days
Table – What to do in case of theft

Question 14: How would you prevent this from happening again?

A) Call the pharmacist who was involved in the incidence
B) Implement employee bag check measures before leaving the pharmacy.
C) Call the regulatory college and report the case
D) Call the Royal Canadian Mounted Police RCMP
E) Report the incidence to the Office of Controlled Substances
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Answer: B

Question 15: Which of the following dosage forms should never be crushed?

a) Sugar coated tablets
b) Chewable tablets
c) Lozenges
d) Osmotic tablets
e) Effervescent tablets
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Answer: D

Crushing an osmotic tablet will lose its integrity and it can no longer function properly.

Question 16: A patient presents to the emergency department with acute glaucoma symptoms, including severe eye pain, blurred vision, and nausea. What is the drug of choice for emergency treatment of glaucoma?

a) Pilocarpine
b) Acetazolamide
c) Dorzolamide
d) Timolol
e) Latanoprost
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Answer: B

Acetazolamide and methazolamide lower IOP by decreasing the production of
aqueous humor. Their use is normally reserved for emergencies because of significant
side effects.

Question 17: What cause QTc prolongation?

a) Citalopram
b) Amiodarone
c) Nitrofurantoin
d) Amoxycillin
e) Captopril
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Answer: A

Question 18: JT is a 45-year-old female who was diagnosed with peptic ulcer. Which of the following is a major risk factor for peptic ulcer in JT’s case?

a) Smoking
b) high fat
c) spicy food
d) DASH diet
e) Uncontrolled diabetes
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Answer: A

Question 19: A 36-year-old male comes to the pharmacy complaining about priapism as it is embarrassing for him. Upon checking his medication records, the pharmacist found that the patient is taking Captopril, Nifedipine XL, and Furosemide for hypertension, Prazosin for nightmares, and Trazodone for sundown syndrome. Which of the following is the most likely cause for this patient’s priapism?

A. Captopril
B. Nifedipine XL
C. Furosemide
D. Prazosin
E. Trazodone
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Answer: E

Question 19: Which of the following drugs cause prerenal failure?

a) Metformin 
b) Furosemide
c) Amoxicillin
d) Omeprazole
e) Pravastatin
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Answer: B

Question 20: Which of the following is an example of fast allergic reaction?

a) Contact dermatitis 
b) Atopic dermatitis
c) Poison ivy
d) Systemic lupus erythematous
e) Blood group transfusion mismatch
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Answer: B

Questions 21-30 to ace PEBC EE

Question 21: What is the mechanism of action of Digoxin?

a) Increases intracellular Calcium
b) Inhibit beta receptor on heart
c) Xanthine Oxidase inhibitor
d) Norepinephrine reuptake promoter
e) Increases intracellular sodium
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Answer: A

Mechanism of ActionEffects
Positive Inotropic EffectIncreases myocardial contractility and efficiency by increasing intracellular calcium levels.

Inhibits membrane-bound Na+/K+-ATPase, leading to increased intracellular sodium and reduced calcium transport out of cells, facilitating calcium entry via voltage-gated channels.
Negative Chronotropic EffectIncreases vagal tone at the sinoatrial node.

Reduces sympathetic outflow from the central nervous system.
Vagomimetic EffectInduces systemic arteriolar and venous constriction.
Table – Digoxin mechanism of action

Question 22: Arylpropionic acid-related compounds such as ibuprofen show which of the following?

a) Streoisomerism
b) homologs
c) conformational isomers
d) structural isomers
e) optical isomers
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Answer: A

Ibuprofen structure
Ibuprofen structure

Question 23: Which of the following drugs has more norepinephrine activity than serotonergic activity?

a) Amitriptyline
b) Fluoxetine
c) Nortriptyline
d) Ibuprofen
e) Amoxicillin
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Answer: C

Question 24: The graph mentioned below represents the data of Fluticasone use and the number of physician visits. X-axis indicates number of physician visits in the last 3 months, and
Y axis represents the patient taking fluticasone for asthma. Which of the following statements is true based on the graph given below?

PEBC EE
A. The patients who use fluticasone in large concentration visited the doctor less frequently
B. The patients who use fluticasone in low concentration visited the doctor less frequently
C. The patients who use fluticasone in large concentration visited the doctor more frequently
D. No relation can be established between fluticasone use and the number of visits to doctor
E. The data is insufficient forfluticasone use
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Answer: A

Question 25: What proportions should be used from 2 ointments containing 0.15% and 0.25% dexamethasone, to make 150 mg dexamethasone of 0.2% of dexamethasone?

A. 15 gm of 2.5% and 45 gm of 0.5% dexamethasone
B. 45 gm of 2.5% and 15 gm of 0.5% dexamethasone
C. 25 gm of 2.5% and 35 gm of 0.5% dexamethasone
D. 35 gm of 2.5% and 25 gm of 0.5% dexamethasone
E. 20 gm of 2.5% and 40 gm of 0.5% dexamethasone
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Answer: A

Use allegation method.

Question 26: A patient came with a prescription in his name. However, upon checking, the pharmacist discovered these drugs didn’t belong to this patient. He asked the patient and found that drugs are for his brother who doesn’t have insurance. If you accept this prescription,which of the following principle you violate?

A. Veracity
B. Autonomy
C. Professional competency
D. Incapacity
E. Equality
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Answer: C

Question 27: In comparison between drug A and drug B in the treatment of smoking cessation, drug A reduces the side effects in 44 patients of 500 patients, and drug B reduces the side effects in 56 patients out of 500 patients. What is the odd ratio?

a) 0.7
b) 1.3
c) 2.6
d) 4.5
e) 3.7
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Answer: A

Question 28: Identify the structure given below from a list of drugs given in the option.

a) Amikacin
b) Warfarin
c) Fluticasone
d) Erythromycin
e) Penicillin
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Answer: A

Question 29: An aliphatic ring can be transformed into a cyclic structure with a lactone ring through which organic reaction?

a) Esterification
b) Friedel-Crafts Alkylation
c) Aldol condensation
d) Lactonization
e) Diels-Alder reaction
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Answer: D

OptionDescription
A) EsterificationFormation of an ester bond between an alcohol and a carboxylic acid.
B) Friedel-Crafts AlkylationAlkylation of aromatic rings using alkyl halides and a strong acid catalyst.
C) Aldol CondensationCondensation of aldehydes and ketones to form a β-hydroxy aldehyde or ketone.
D) LactonizationFormation of a lactone ring by adding an oxygen across a carbon-carbon double bond in an aliphatic ring.
E) Diels-Alder ReactionCycloaddition reaction between a conjugated diene and a substituted alkene, forming a six-membered ring.
Table – Explanation of reactions

Question 30: In a clinical trial of a drug to prevent migraines, 2 out of 100 people taking the drug experience a migraine (2%), compared with 4 out of 100 people taking a placebo (4%). Based on the given information, answer the following questions.

Question 30.1: What is the Absolute Risk Reduction (ARR) in this clinical trial?

A) 0.5%
B) 1%
C) 2%
D) 3%
E) 4%
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Answer: C

The Absolute Risk Reduction (ARR) is the difference in risk between the control group and the treatment group.

  • ARR = 4% (placebo group) – 2% (treatment group) = 2%

Question 30.2: What is the Relative Risk Reduction (RRR) in this clinical trial?

A) 25%
B) 50%
C) 75%
D) 100%
E) 125%
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Answer: B

The Relative Risk Reduction (RRR) is the ARR divided by the risk in the control group.

  • RRR = ARR / Risk in control group = 2% / 4% = 50%

Question 30.3: What is the Number Needed to Treat (NNT) in this clinical trial?

A) 25
B) 50
C) 75
D) 100
E) 200
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Answer: B

The Number Needed to Treat (NNT) is the inverse of the ARR.

  • NNT = 1 / ARR = 1 / 0.02 = 50

This comprehensive guide equips you with solved questions and exam-mimicking strategies to conquer the PEBC EE Exam. Gain confidence in drug-drug interaction, drug-disease interaction, and other question types. Excel with PEBC EE Exam-styled questions. Start your PEBC EE exam preparation today!

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